WebNotably, protein levels of EGR1 also increased shortly after AREG stimulation in DVL3 tumor cells (Figures S6 A and S6D), suggesting posttranslational stabilization of EGR1 by AREG. AREG-mediated ERK1/2 activation and EGR1 upregulation could be suppressed by pre-treatment of cells with the MEK inhibitor trametinib (Figures 6 A, and S6 E). The DNA-binding domain of EGR-1 consists of three zinc finger domains of the Cys2His2 type. The amino acid structure of the EGR-1 zinc finger domain is given in this table, using the single letter amino acid code. The fingers 1 to 3 are indicated by f1 - f3. The numbers are in reference to the residues (amino acids) of alpha helix (there is no zero). The residues marked 'x' are not part of the zinc fingers, but rather serve to connect them all together.
The zebrafish egr1 gene encodes a highly conserved, zinc-finger ...
WebJun 23, 2024 · Another ELK1-dependent IEG, EGR1, is involved in memory consolidation 280,281. The ERK-inhibited transcriptional repressor CIC is also crucially involved in … WebMar 21, 2024 · EGR1 (Early Growth Response 1) is a Protein Coding gene. Diseases associated with EGR1 include Ischemia and Monocytic Leukemia. Among its related pathways are PIP3 activates AKT signaling and … costo risonanza magnetica caviglia
EGR1 as a potential marker of prognosis in extranodal NK/T-cell ...
WebJan 13, 2024 · EGR1 is essential for monopoiesis and binds enhancers that regulate monocytic developmental genes such as CSF1R However, differentiating macrophages … WebJun 25, 2024 · EGR1 Antibody (B-6) is an IgG1 κ mouse monoclonal Egr-1 antibody that detects m, r, and h Egr-1 p82 by WB, IP, IF and ELISA. 12 citations ... Rated 5 out of 5 … WebJan 1, 2014 · EGR1 is a target of ETS transcription factors that are involved in hematopoiesis, angiogenesis and neoplasia. Finally, EGR1 promoter contains two ATF5 (activating transcription factor 5) consensus sequences at a conserved promoter position and is induced by ATF5 in cancer cell lines. Proteins Figure 1. Description macon tele obit